Several new studies demonstrate the power of vitamin D to reduce inflammation and pain, operating at the DNA level to regulate genes to reduce inflammation.  This information expands our understanding of vitamin D in relation to the immune response and sends a clear message that people with any kind of pain or ongoing inflammation should optimize their vitamin D levels as a key aspect of solving inflammatory problems.

We have known for some time that vitamin D is needed for optimal immune performance, whether combating pain or fighting the flu.  It is well established that vitamin D is the single most important substance in your body for something called immune system tolerance.  Such a concept is highly relevant to fighting infection and pain.

Vitamin D and Inflammation

Researchers from National Jewish Health reporting in The Journal of Immunology have discovered specific molecular and signaling events by which vitamin D inhibits inflammation to help prevent and possibly even treat a host of potentially deadly diseases. Current levels considered satisfactory by most medical professionals did not inhibit the inflammatory cascade, leading to the progression of many forms of disease. Conversely, individuals that maintain significantly higher blood levels of vitamin D had lower levels of inflammatory markers known to aggravate disease progression and were protected against the major killers so prevalent today.

How Much Vitamin D

Researchers identified a new location where the vitamin-D receptor appears to bind directly to DNA and activate a gene known as MKP-1, interfering with the inflammatory cascade promoted by long-term stress and a highly refined, processed food diet. Maintain your vitamin D blood levels above 50 ng/ml (measured with the 25(OH)D test) to afford maximum protection against chronic inflammatory-mediated diseases.

Sources:

http://articles.mercola.com/sites/articles/archive/2004/02/28/vitamin-d-part-twenty.aspx

http://www.naturalnews.com/035694_vitamin_D_inflammatory_disease_prevention.html#ixzz2aAALPnRl

http://www.wellnessresources.com/health/articles/vitamin_d_is_a_powerful_anti-inflammatory/